Disentangling Macromolecular Assemblies in
Healthy Aging and Neurodegeneration

PREVENTING GOOD BIOLOGY FROM DOING BAD THINGS. The Sanders Lab is based in the Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern. Our mission is to illuminate how failures in RNA and protein homeostasis trigger diseases of aging, from ALS and Alzheimer’s disease to Parkinson’s and myopathies. Most of our studies are performed in close collaboration with Sarah Shahmoradian’s group. The Sanders Lab’s unique cellular and neuronal models of RNA/protein aggregation integrate with the Shahmoradian Lab’s cutting-edge, structural technologies to discover why neurodegenerative diseases start and how they might be stopped!

We are recruiting at all levels. If you are passionate about curiosity-based research at the interface of health and disease, please reach out to David and Sarah by e-mail and include a paragraph about why you are excited about potentially joining the group! Please see Projects and Publications for details on current and past work!


REACH OUT! We are always looking for collaborators! Email David and Sarah to discuss!