Publications
Sanders Lab Productions
Stay tuned! This could be YOU!
DW Sanders Post-Doc Publications
Princeton University
Advisor: Cliff Brangwynne
*Co-first authors
(18) Condensate interfaces can accelerate protein aggregation
C-H Choi, DSW Lee, DW Sanders, CP Brangwynne
Biophysical Journal (2023)
(17) Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions
J Park, Y Wu, W Shao, TF Gendron, SJF van der Spek, G Sultanakhmetov, A Basu, PC Otero, CJ Jones, K Jansen-West, LM Daughrity, S Phanse, G del Rosso, J Tong, M Castanedes-Casey, L Jiang, J Libera, B Oskarsson, DW Dickson, DW Sanders, CP Brangwynne, A Emili, B Wolozin, L Petrucelli, YJ Zhang
Cell Reports (2023)
(16) Size distributions of intracellular condensates reflect competition between coalescence and nucleation
DSW Lee, CH Choi, DW Sanders, L Beckers, JA Riback, CP Brangwynne, NS Wingreen
Nature Physics (2023)
Biorxiv (Pre-print, Mar. 2022)
(15) SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
DW Sanders*, CC Jumper*, PJ Ackerman*, D Bracha, A Donlic, H Kim, D Kenney, S Suzuki, T Tamura, I Castello-Serrano, AH Tavares, M Saeed, AS Holehouse, A Ploss, I Levental, F Douam, RF Padera, BD Levy, CP Brangwynne
eLife (2021)
Biorxiv (Pre-Print, Dec. 2020)
[PDF-Main] [PDF-Supp]
[HHMI News Story]
[Presentation by Cliff]
[THE Medical News Article]
[Speak Russian? David doesn’t. But Grisha does]
(14) Nucleation landscape of biomolecular condensates
SF Shimobayashi, P Ronceray, DW Sanders, MP Haataja, CP Brangwynne
Nature (2021)
(13) Competing protein-RNA interaction networks control multiphase intracellular organization
DW Sanders, N Kedersha, DSW Lee, AR Strom, V Drake, JA Riback, D Bracha, JM Eeftens, A Iwanicki, A Wang, MT Wei, G Whitney, SM Lyons, P Anderson, WM Jacobs, P Ivanov, CP Brangwynne
Cell (2020)
[PDF-Main] [PDF-Supp]
[Preview By Ashok Deniz]
[Princeton Press Release]
[Princeton Insights Coverage]
[Fist-Bump from Mike Rosen in Science ]
[Nature News-Building Out]
(12) Composition dependent thermodynamics of intracellular phase separation
JA Riback, L Zhu, MC Ferrolino, M Tolbert, DM Mitrea, DW Sanders, MT Wei, RW Kriwacki, CP Brangwynne
Nature (2020)
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[PDF]
[Preview By Chiu Fan Lee]
[Princeton Press Release]
(11) Liquid nuclear condensates mechanically sense and restructure the genome
Y Shin, YC Chang, DSW Lee, J Berry, DW Sanders, P Ronceray, NS Wingreen, M Haataja, CP Brangwynne
Cell (2018)
[PDF]
[Preview By Tuomas Knowles]
[Nature Methods Overview]
[Princeton Press Release]
(10) COMMENTARY: Neurodegenerative disease: RNA repeats put a freeze on cells
DW Sanders & CP Brangwynne
Nature (2017)
[PDF]
See original paper from Jain &Vale!
DW Sanders Grad School Publications
Washington University in St. Louis
Advisor: Marc Diamond
*Co-first authors
(8) The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
I Saha, P Yuste-Checa, M Da Silva Padilha, Q Guo, R Körner, H Holthusen, VA Trinkaus, I Dudanova, R Fernández-Busnadiego, W Baumeister, DW Sanders, S Gautam, MI Diamond, FU Hartl, MS Hipp
Nature Communications (2023)
Biorxiv (Pre-print, Feb 2022)
(7) The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition
G Eskandari-Sedighi, N Daude, H Gapeshina, DW Sanders, R Kamali-Jamil, J Yang, B Shi, H Wille, B Ghetti, MI Diamond, C Janus, D Westaway
Molecular Neurodegeneration (2017)
[PDF]
(6) Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo
SK Kaufman*, DW Sanders*, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, AM Sharma, TM Miller, MI Diamond
Neuron (2016)
[PDF]
[UT Southwestern Press Release]
[AlzForum Coverage]
(5) Neuronal activity enhances tau propagation and tau pathology in vivo
JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, DW Sanders, C Cook, H Fu, RACM Boonen, M Herman, E Nahmani, S Emrani, YH Figueroa, MI Diamond, CL Clelland, S Wray, KE Duff
Nature Neuroscience (2016)
[PDF]
[Columbia Press Release]
[AlzForum Coverage]
(2) Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation
H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond
Journal of Biological Chemistry (2015)
[PDF]
[Alzforum Coverage]
(1) Distinct tau prion strains propagate in cells and mice and define different tauopathies.
DW Sanders*, SK Kaufman*, SL DeVos, AM Sharma, H Mirbaha, A Li, SJ Barker, AC Foley, JR Thorpe, LC Serpell, TM Miller, LT Grinberg, WW Seeley, MI Diamond
Neuron (2014)
[PDF]
[Preview by Brad Hyman]
[WashU Press Release]
[AlzForum Coverage of Paper]
[AlzForum Coverage of Prelim Data]
SEE PROJECTS FOR ONGOING WORK!